Table 5 Cox-regression models assessing the potential of clinical and epigenetics variables in the prediction of disease-specific survival in cohort #1
Disease-specific survival | Variable | Hazard ratio (HR) | 95% CI for OR | P value |
|---|---|---|---|---|
Multivariable | Clinical stage | |||
III/IV | 9.637 | 2.597–35.763 | 0.001 | |
Panel #1: miR-34b/c | ||||
Promoter methylation > P75 | 3.843 | 1.268–11.649 | 0.017 | |
Clinical stage | ||||
III/IV | 8.334 | 2.274–30.548 | 0.001 | |
Panel #2 | ||||
Promoter methylation > P75 | 3.786 | 1.038–13.810 | 0.044 | |