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Table 4 Diagnostic performance of DNA methylation-based biomarkers in cohort #2

From: Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients

Parameters

Panel #1

Panel #2

Panels #1 and #2

Sensitivity %

95.4

94.3

100.0

Specificity %

84.4

84.4

75.0

Positive predictive value %

94.3

94.3

91.6

Negative predictive value %

87.1

84.4

100.0

Accuracy %

92.4

91.6

93.3

Positive likelihood ratio (LR+)

6.12

6.04

4.00

Negative likelihood ratio (LR−)

0.05

0.07

-