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Table 3 Diagnostic performance of DNA methylation-based biomarkers in cohort #1

From: Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients

Parameters

Panel #1

Panel #2

Sensitivity %

97.3

100.0

Specificity %

80.0

100.0

Positive predictive value %

96.0

100.0

Negative predictive value %

85.7

100.0

Accuracy %

94.4

100.0

Positive likelihood ratio (LR+)

4.87

Negative likelihood ratio (LR−)

0.03