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Fig. 3 | Clinical Epigenetics

Fig. 3

From: The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes

Fig. 3

Impact of shBCL2L11 leukemia cell lines on apoptosis induced by quercetin. a BCL2L11 mRNA relative expressions in sh BCL2L11 U937 and HL60 cell lines. b Western blotting was performed for BCL2L11in sh control and sh BCL2L11 U937 and HL60 cell lines. c sh control and sh BCL2L11 U937 and HL60 cell lines were treated with 50 μmol/L Qu for 48 h, after treatment cells were stained with annexin V/PI. The percentage of apoptotic cells were determined by flow cytometry. Values are expressed as mean ± SD. *p < 0.05; **p < 0.005 when compared to sh control cell lines. All data were representative of three independent experiments

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