Fig. 1
From: Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma
SUV39H2 was upregulated in lung adenocarcinoma. a The raw data of “GSE19084” chip assay was downloaded from GEO datasets and analyzed via R software. The samples were grouped into adjacent normal tissues and tumor tissues in a pair-wise manner, and the expressions of the indicated genes were analyzed in the eBayes manner. The heatmap profiled the mRNA expression of the indicated genes, and the genes with higher expression (p < 0.001) in the specimen are highlighted in red, and those with lower expression are highlighted in blue. b The CNA data of SUV39H1 and SUV39H2 were sorted from the Lung Adenocarcinoma (TCGA, Provisional) dataset of TCGA. The amplification percentages of the indicated genes in each tumor stage were analyzed according to the clinical data. c Different CNA statuses of SUV39H2 were plotted against the corresponding mRNA expressions of the gene, demonstrating a gradual rise as the CNA status leveled up. Correlation of each indicated pair was assessed via nonparametric test. **p < 0.01, *p < 0.05. d Kaplan-Meier plots of overall survival associated with the mRNA expression level of SUV39H2 in TCGA lung adenocarcinomas