Table 1 Participants’ characteristics
| Â | Non-IRR | TBI/HSCT | p value (TBI/HSCT vs non-IRR) |
|---|---|---|---|
Number of participants | 30 | 14 | Â |
Sex (male/female) | 15/15 | 9/5 | 0.25 |
Age (year, range) | 22.1 (16–34) | 25.1 (16–39) | 0.48 |
Age at diagnosis (year, range) | 7.2 (0.2–17.7) | 7.7 (1.2–16.6) | 0.78 |
Height (cm) | 170 ± 9 | 163 ± 12 | 0.05 |
Weight (kg) | 73.9 ± 18.8 | 62.0 ± 19.3 | 0.07 |
Body mass index (kg/m2) | 25.5 ± 5.7 | 23.2 ± 6.8 | 0.26 |
Waist-to-height ratio | 50.8 ± 8.5 | 51.4 ± 11.1 | 0.84 |
Diagnosis (number of survivors, %) | |||
 Acute lymphoblastic leukemia | 12 (40%) | 5 (36%) |  |
  Relapse | 0 (0%) | 1 (7%) |  |
 Acute myeloid leukemia | 1 (3%) | 6 (43%) |  |
  Relapse | 0 (0%) | 1 (7%) |  |
 Neuroblastoma | 1 (3%) | 2 (14%) |  |
 Malignant histiocytosis | 0 (0%) | 1 (7%) |  |
 Hodgkins lymphoma | 2 (13%) | 0 (0%) |  |
 Non-Hogkins lymphoma | 3 (10%) | 0 (0%) |  |
 Other type of cancer | 11 (21%) | 0 (0%) |  |
Treatments (number of survivors, %) | |||
 Chemotherapy | 30 (100%) | 14 (100%) |  |
 TBI | 0 (0%) | 14 (100%) |  |
 Hematopoietic stem cell transplant | 3 (10%) | 14 (100%) |  |
Triglycerides (mmol/l) | 1.03 ± 0.50 | 2.11 ± 2.08 | 0.01 |
Total cholesterol (mmol/l) | 4.82 ± 0.79 | 5.14 ± 1.12 | 0.28 |
LDL-cholesterol (mmol/l) | 2.86 ± 0.53 | 2.97 ± 1.13 | 0.67 |
HDL-cholesterol (mmol/l) | 1.59 ± 0.71 | 1.17 ± 0.41 | 0.05 |
Glucose (mmol/l) | 4.74 ± 0.47 | 6.04 ± 4.19 | 0.10 |
Insulin (mIU/l) | 7.17 ± 5.76 | 11.3 ± 8.60 | 0.07 |
HOMA-IR | 0.96 ± 0.73 | 1.84 ± 1.98 | 0.04 |