IlmnID | CHR | Location | Gene name | Non-smoker | Current smoker | Coef. | S.E. | P value | cis-meQTL | S* |
---|---|---|---|---|---|---|---|---|---|---|
β (mean ± SD) | β (mean ± SD) | |||||||||
cg05951221 | 2 | 233284402 | 2q37.1 | 0.255 ± 0.054 | 0.172 ± 0.040 | − 1.380 | 0.108 | 1.28 × 10−29 | rs2853386; 3.87 × 10−8 | |
cg21566642 | 2 | 233284661 | 2q37.1 | 0.225 ± 0.040 | 0.167 ± 0.029 | − 1.347 | 0.122 | 1.87 × 10−23 | ||
cg23680900 | 15 | 75017924 | CYP1A1 | 0.202 ± 0.036 | 0.155 ± 0.030 | − 1.198 | 0.118 | 2.96 × 10−21 | O | |
cg14120703 | 9 | 139416102 | NOTCH1 | 0.748 ± 0.045 | 0.693 ± 0.044 | − 1.172 | 0.118 | 1.44 × 10−20 | ||
cg26516004 | 15 | 75019376 | CYP1A1 | 0.696 ± 0.047 | 0.628 ± 0.058 | − 1.258 | 0.126 | 1.95 × 10−20 | Y | |
cg10009577 | 15 | 75018150 | CYP1A1 | 0.068 ± 0.021 | 0.050 ± 0.016 | − 0.810 | 0.090 | 2.48 × 10−17 | Y | |
cg01985595 | 6 | 136479501 | PDE7B | 0.961 ± 0.025 | 0.936 ± 0.032 | − 1.015 | 0.119 | 1.09 × 10−15 | Y | |
cg22418620 | 5 | 172072885 | NEURL1B | 0.832 ± 0.049 | 0.765 ± 0.057 | − 1.077 | 0.127 | 1.63 × 10−15 | rs57285944; 2.15 × 10−8 | Y |
cg23160522 | 15 | 75015787 | CYP1A1 | 0.622 ± 0.033 | 0.583 ± 0.044 | − 0.991 | 0.122 | 1.33 × 10−14 | Y | |
cg03636183 | 19 | 17000585 | F2RL3 | 0.506 ± 0.040 | 0.473 ± 0.038 | − 0.826 | 0.103 | 1.80 × 10−14 | ||
cg07992500 | 2 | 37896583 | CDC42EP3 | 0.771 ± 0.051 | 0.719 ± 0.052 | − 1.087 | 0.141 | 1.88 × 10−13 | rs7595854; 1.32 × 10−7 | |
cg12531611 | 6 | 11212619 | NEDD9 | 0.909 ± 0.021 | 0.892 ± 0.024 | − 0.855 | 0.120 | 1.12 × 10−11 | O | |
cg03646542 | 5 | 172076155 | NEURL1B | 0.689 ± 0.037 | 0.654 ± 0.035 | − 0.880 | 0.133 | 1.87 × 10−10 | rs7715699; 1.72 × 10−10 | Y |
cg00353139 | 15 | 75017914 | CYP1A1 | 0.034 ± 0.013 | 0.022 ± 0.010 | − 0.787 | 0.121 | 4.47 × 10−10 | rs11072498; 2.47 × 10−6 | Y |
cg21124714 | 11 | 72983097 | P2RY6 | 0.736 ± 0.037 | 0.707 ± 0.033 | − 0.874 | 0.136 | 5.15 × 10−10 | Y | |
cg01940273 | 2 | 233284934 | 2q37.1 | 0.334 ± 0.045 | 0.302 ± 0.044 | − 0.679 | 0.105 | 8.93 × 10−10 | ||
cg25648203 | 5 | 395444 | AHRR | 0.503 ± 0.044 | 0.459 ± 0.040 | − 0.825 | 0.132 | 1.30 × 10−9 | ||
cg20408276 | 2 | 38300586 | CYP1B1 | 0.548 ± 0.060 | 0.499 ± 0.059 | − 0.781 | 0.125 | 1.61 × 10−9 | O | |
cg20131897 | 12 | 52305332 | ACVRL1 | 0.694 ± 0.034 | 0.673 ± 0.028 | −0.693 | 0.116 | 5.61 × 10−9 | rs1700159; 2.97 × 10−7 | Y |
cg21611682 | 11 | 68138269 | LRP5 | 0.370 ± 0.041 | 0.336 ± 0.035 | −0.734 | 0.124 | 8.10 × 10−9 | ||
cg19405895 | 5 | 407315 | AHRR | 0.955 ± 0.014 | 0.942 ± 0.024 | −0.768 | 0.128 | 8.38 × 10−9 | Y | |
cg05575921 | 5 | 373378 | AHRR | 0.713 ± 0.044 | 0.682 ± 0.039 | − 0.611 | 0.104 | 1.07 × 10−8 | rs7731963; 3.97 × 10−8 | |
cg13531977 | 9 | 112013420 | EPB41L4B | 0.807 ± 0.035 | 0.833 ± 0.029 | 0.831 | 0.140 | 1.14 × 10−8 | Y | |
cg00512031 | 4 | 5021976 | CYTL1 | 0.880 ± 0.026 | 0.855 ± 0.028 | −0.760 | 0.129 | 1.23 × 10−8 | chr4:5022470;1.42 × 10−9 | Y |
cg25189904 | 1 | 68299493 | GNG12 | 0.100 ± 0.043 | 0.064 ± 0.030 | − 0.771 | 0.131 | 1.48 × 10−8 | ||
cg00378510 | 19 | 2291020 | LINGO3 | 0.217 ± 0.059 | 0.181 ± 0.053 | −0.781 | 0.134 | 1.53 × 10−8 | rs12609156; 6.83 × 10−18 | |
cg11554391 | 5 | 321320 | AHRR | 0.065 ± 0.019 | 0.048 ± 0.014 | −0.720 | 0.125 | 2.00 × 10−8 | ||
cg01802380 | 13 | 107865407 | FAM155A | 0.845 ± 0.030 | 0.825 ± 0.037 | −0.737 | 0.133 | 5.69 × 10−8 | rs9520326; 1.52 × 10−12 | Y |
cg14179389 | 1 | 92947961 | GFI1 | 0.083 ± 0.030 | 0.063 ± 0.028 | −0.665 | 0.122 | 1.07 × 10−7 | ||
cg06644428 | 2 | 233284112 | 2q37.1 | 0.036 ± 0.018 | 0.024 ± 0.010 | − 0.704 | 0.130 | 1.61 × 10−7 | ||
cg12081267 | 2 | 98486185 | TMEM131 | 0.878 ± 0.038 | 0.858 ± 0.035 | − 0.650 | 0.122 | 1.97 × 10−7 | Y | |
cg02162897 | 2 | 38300537 | CYP1B1 | 0.567 ± 0.060 | 0.520 ± 0.061 | −0.674 | 0.127 | 2.89 × 10−7 | O | |
cg11555067 | 2 | 99081350 | INPP4A | 0.725 ± 0.047 | 0.700 ± 0.046 | −0.717 | 0.138 | 3.18 × 10−7 | rs3754893; 2.27 × 10−7 | |
cg04134818 | 5 | 148998446 | FLJ41603 | 0.153 ± 0.026 | 0.133 ± 0.025 | −0.690 | 0.132 | 3.26 × 10−7 | rs11950259; 7.83 × 10−6 | Y |
cg03976650 | 13 | 77456505 | KCTD12 | 0.667 ± 0.061 | 0.612 ± 0.067 | −0.754 | 0.143 | 3.56 × 10−7 | Y | |
cg22851561 | 14 | 74214183 | C14orf43 | 0.422 ± 0.041 | 0.390 ± 0.040 | −0.634 | 0.121 | 3.92 × 10−7 | ||
cg10376100 | 1 | 236017278 | LYST;MIR1537 | 0.923 ± 0.036 | 0.947 ± 0.030 | 0.615 | 0.117 | 4.03 × 10−7 | Y | |
cg04063216 | 2 | 14772482 | FAM84A | 0.071 ± 0.016 | 0.075 ± 0.019 | 0.441 | 0.085 | 4.39 × 10−7 | Y | |
cg16320419 | 3 | 5025570 | BHLHE40 | 0.352 ± 0.052 | 0.315 ± 0.048 | − 0.699 | 0.135 | 4.88 × 10−7 | ||
cg04135110 | 5 | 346695 | AHRR | 0.339 ± 0.061 | 0.384 ± 0.065 | 0.699 | 0.137 | 5.34 × 10−7 | rs2672748; 3.42 × 10−17 | |
cg20109054 | 6 | 31804109 | C6orf48;SNORD52 | 0.091 ± 0.026 | 0.072 ± 0.023 | − 0.659 | 0.130 | 7.85 × 10−7 | rs3828922; 2.74 × 10−5 | |
cg16721845 | 11 | 68518800 | MTL5 | 0.018 ± 0.008 | 0.014 ± 0.007 | − 0.530 | 0.106 | 8.37 × 10−7 | Y |