Fig. 6
From: The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer
Re-expression of DACOR1 in V852 colon cancer cells results in genome-wide changes in DNA methylation. a The patient-derived colon cancer cell line V852 was transduced with either an empty vector lentivirus or a lentivirus containing the full-length DACOR1, and DNA methylation was examined by RRBS assay under both conditions (n = 3 of each condition). b Distribution of changes in DNA methylation in V852 cells in response to DACOR1 induction. c Over 17,000 CpG sites are affected by DACOR1 induction with the vast majority of sites (99.9%) showing gain of methylation