Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

Table 4 Methylation levels of specific sites between cases and controls

Gene	Fragment	Methylation level of controls (n = 118)		Methylation level of cases (n = 122)
Gene	Fragment	Mean ± SD	Median	Mean ± SD	Median
CYP24A1	CYP24A1_1	0.39 ± 0.13	0.374	0.35 ± 0.12	0.335
CYP24A1	CYP24A1_2	0.48 ± 0.08	0.461	0.41 ± 0.07	0.397
CYP27A1	CYP27A1_1	0.87 ± 0.23	0.818	0.75 ± 0.27	0.678
	CYP27A1_2	0.78 ± 0.24	0.716	0.63 ± 0.24	0.557
	CYP27A1_3	0.54 ± 0.20	0.508	0.43 ± 0.18	0.398
	CYP27A1_4	0.72 ± 0.17	0.697	0.63 ± 0.12	0.606
	CYP27A1_5	1.79 ± 0.20	1.804	1.76 ± 0.01	1.784
CYP27B1	CYP27B1_1	3.22 ± 0.56	3.167	2.78 ± 0.56	2.664
	CYP27B1_2	1.56 ± 0.33	1.493	1.40 ± 0.32	1.345
	CYP27B1_3	0.60 ± 0.14	0.578	0.53 ± 0.14	0.499
CYP2R1	CYP2R1_1	0.13 ± 0.01	0.129	0.13 ± 0.01	0.126
	CYP2R1_2	0.15 ± 0.01	0.152	0.15 ± 0.01	0.148
	CYP2R1_3	0.22 ± 0.05	0.223	0.22 ± 0.05	0.213
	CYP2R1_4	0.13 ± 0.02	0.124	0.12 ± 0.01	0.123
VDR	VDR _1	0.94 ± 0.23	0.897	0.82 ± 0.23	0.781
	VDR _2	0.37 ± 0.05	0.362	0.33 ± 0.06	0.313
	VDR _3	0.21 ± 0.10	0.196	0.20 ± 0.10	0.188
	VDR _4	0.13 ± 0.02	0.132	0.12 ± 0.02	0.122
	VDR _6	0.26 ± 0.07	0.270	0.27 ± 0.07	0.263

ISSN: 1868-7083