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Table 4 Methylation levels of specific sites between cases and controls

From: Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

Gene Fragment Methylation level of controls (n = 118) Methylation level of cases (n = 122)
Mean ± SD Median Mean ± SD Median
CYP24A1 CYP24A1_1 0.39 ± 0.13 0.374 0.35 ± 0.12 0.335
CYP24A1_2 0.48 ± 0.08 0.461 0.41 ± 0.07 0.397
CYP27A1 CYP27A1_1 0.87 ± 0.23 0.818 0.75 ± 0.27 0.678
CYP27A1_2 0.78 ± 0.24 0.716 0.63 ± 0.24 0.557
CYP27A1_3 0.54 ± 0.20 0.508 0.43 ± 0.18 0.398
CYP27A1_4 0.72 ± 0.17 0.697 0.63 ± 0.12 0.606
CYP27A1_5 1.79 ± 0.20 1.804 1.76 ± 0.01 1.784
CYP27B1 CYP27B1_1 3.22 ± 0.56 3.167 2.78 ± 0.56 2.664
CYP27B1_2 1.56 ± 0.33 1.493 1.40 ± 0.32 1.345
CYP27B1_3 0.60 ± 0.14 0.578 0.53 ± 0.14 0.499
CYP2R1 CYP2R1_1 0.13 ± 0.01 0.129 0.13 ± 0.01 0.126
CYP2R1_2 0.15 ± 0.01 0.152 0.15 ± 0.01 0.148
CYP2R1_3 0.22 ± 0.05 0.223 0.22 ± 0.05 0.213
CYP2R1_4 0.13 ± 0.02 0.124 0.12 ± 0.01 0.123
VDR VDR _1 0.94 ± 0.23 0.897 0.82 ± 0.23 0.781
VDR _2 0.37 ± 0.05 0.362 0.33 ± 0.06 0.313
VDR _3 0.21 ± 0.10 0.196 0.20 ± 0.10 0.188
VDR _4 0.13 ± 0.02 0.132 0.12 ± 0.02 0.122
VDR _6 0.26 ± 0.07 0.270 0.27 ± 0.07 0.263