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Table 10 Crossover analysis of CYP27A1 methylation levels and 1,25-dihydroxyvitamin D levels in the sputum conversion of patients with TB

From: Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

1,25(OH)2Da

Cumulative methylation levelb

Sputum conversion

OR

95% CI

Yes

No

Low

High

9

3

0.27

0.02–3.09

High

High

10

4

0.23

0.02–2.39

Low

Low

11

4

0.25

0.02–2.61

High

Low

11

1

1

 
  1. aCutoff point of 1,25(OH)2D 79 pmol/L
  2. bCutoff point of cumulative methylation level of CYP27A1 0.435