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Table 10 Crossover analysis of CYP27A1 methylation levels and 1,25-dihydroxyvitamin D levels in the sputum conversion of patients with TB

From: Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis

1,25(OH)2Da Cumulative methylation levelb Sputum conversion OR 95% CI
Yes No
Low High 9 3 0.27 0.02–3.09
High High 10 4 0.23 0.02–2.39
Low Low 11 4 0.25 0.02–2.61
High Low 11 1 1  
  1. aCutoff point of 1,25(OH)2D 79 pmol/L
  2. bCutoff point of cumulative methylation level of CYP27A1 0.435