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Fig. 2 | Clinical Epigenetics

Fig. 2

From: FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression

Fig. 2

Genome-wide Manhattan plot for arachidonic acid (a), gamma-linolenic acid (b), and adrenic acid (c). Plots of –log10(P) values for associations tested by linear regression analysis with adjustments for age, sex, and BMI under an additive genetic model against fatty acid levels across the entire autosomal genome are shown. The red dots at each locus indicate the signals with P < 10−4 detected in the genome-wide analysis. A total of 32,387 SNPs was used to generate the plots. FADS, fatty acid desaturase; ARHGAP5, P190-B RhoGAP; FAM107B, family with sequence similarity 107 member B

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