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Table 4 Statistics for the comparison of saliva BDNF methylation in BPD patients before and after therapy

From: Increased BDNF methylation in saliva, but not blood, of patients with borderline personality disorder

CpG site

Mean difference

CI lower

CI upper

p value

Cohen’s d

CpG11:27723161

− 0.7

− 1.303

− 0.011

0.047

0.4

CpG11:27723159

− 0.6

− 1.562

0.282

0.165

n.a.

CpG11:27723143

− 1.4

− 2.542

− 0.324

0.013

0.5

CpG11:27723137

− 0.0

− 0.660

0.561

0.871

n.a.

Average

− 0.7

− 1.370

− 0.019

0.044

0.4

  1. Results of paired t tests for salivary BDNF IV promoter methylation in BPD patients before (T1) and after treatment (T2) (N = 26). Results shown for individual CpG sites and for the average calculated from all sites
  2. n.a. not applicable (p value > 0.05)
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Clinical Epigenetics

ISSN: 1868-7083

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