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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Increased BDNF methylation in saliva, but not blood, of patients with borderline personality disorder

Fig. 3

BDNF IV promoter methylation in BPD patients before and after a 12-week psychotherapeutic treatment in saliva (ac, N = 26) and blood (df, N = 23). Data shown for single CpG sites (a, d) and for the average calculated from all analyzed CpG sites (b, c, e, f), Data points are displayed as mean ± SEM of all patients at the two time points. Statistical analysis has been conducted with paired t tests. Asterisks indicate significance p < 0.05 (a, b, d, e). Individual differences in DNA methylation levels before and after treatment shown for every patient in saliva (c) and blood (f)

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