Fig. 5
From: Epigenetic regulation of ID4 in breast cancer: tumor suppressor or oncogene?
Phenotypic changes associated with ectopic ID4 expression in breast cancer cell lines. a Bar graph presentation of wound healing assay comparisons. The effect of ectopic expression of ID4 was tested on cell migration ability in MCF-7 and T47D cell lines (left and right respectively). Columns represent the mean of at least three independent experiments. *p < 0.05 and **p < 0.01 in comparison with the control per Student’s t test. For migration experiments, cells were maintained in a serum-reduced medium to inhibit the cells’ ability to proliferate. b Colony formation assay was used to confirm the effect of ID4 expression in T47D and MCF-7 transfected either with ID4 or the control vector. Results are expressed as the mean ± SD of three independent experiments