Table 2 List of top enriched biological processes identified from gene ontology study with the differential promoters
From: Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis
GO term: biological process | Gene count (%) | Fold enrichment | P value (BH) |
|---|---|---|---|
Regulation of immune system process | 14.11 | 2.11 | 4.40 × 10−9 |
T cell activation | 6.31 | 2.91 | 4.90 × 10−7 |
Regulation of cell adhesion | 7.81 | 2.50 | 6.89 × 10−7 |
Regulation of leukocyte activation | 5.71 | 2.51 | 4.38 × 10−5 |
Inflammatory response | 7.66 | 2.48 | 1.11 × 10−6 |
Cell migration | 12.76 | 2.22 | 5.20 × 10−9 |
Regulation of cell migration | 7.21 | 2.17 | 7.15 × 10−5 |
Leukocyte migration | 5.40 | 2.96 | 2.77 × 10−6 |
Neutrophil migration | 2.40 | 5.26 | 2.86 × 10−5 |
Positive regulation of MAPK cascade | 5.56 | 2.36 | 1.85 × 10−4 |
Extracellular matrix organisation | 3.90 | 2.41 | 3.43 × 10−3 |