Fig. 1
From: Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis
Characterisation of differentially methylated probes (DMPs) (N = 4133). a Classification of the DMPs into hyper- and hypomethylated probes. b Distribution of the hyper- and hypomethylated probes across different genomic regions. c Hierarchical clustering with 4133 DMPs shows distinctly separate clusters for disease and adjacent normal samples. Normal samples are marked in light green, and disease samples are marked in dark green. d Overlap of DMPs with psoriasis susceptibility regions (PSORS) and non-PSORS. e Distribution of PSORS-overlapping DMPs across various known PSORS loci. Loci significantly enriched (P value ≤ 0.05) in hypergeometric test are marked (*)