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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Increased CD4+ T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients

Fig. 5

Case studies of lymph nodes with low or high methylation in IFNG locus. a Same as Fig. 2a, with evaluated lymph nodes circled in red. bd Bar graphs depicts percentage of demethylation levels at the four signature sites, representing increase in lineage commitment. Th1 = IFNG, Th2 = IL13, Treg = FOXP3, Th17 = IL17A. b LN from three patients with high IFNG methylation. c LNs from two patients with low IFNG methylation patterns. d Case study of three LNs from patient no. 6, chosen for a distinct IFNG demethylation in one node (from Fig. 5c, lower bars)

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