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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Increased CD4+ T cell lineage commitment determined by CpG methylation correlates with better prognosis in urinary bladder cancer patients

Fig. 1

Sorting strategy and loci visualization. a CD3+ cells derived from PBMC, lymph nodes or tumour tissue were sorted by flow cytometry using a FACSARIA. Gating strategy was done as follows: singlets > lymphocytes > CD56 > CD4+. CD4+CD56. Purity analysis is presented in percentage of parent. Plots show representative best. b Signature loci visualized by VISTA-plots. The conservation of the assessed gene loci between human and mouse is depicted relative to the genes. The conservation is defined as stretches of nucleotides more than 100 bp with over 70% conserved area. The magnified area schematically describes the investigated regions. Analysed CpG is marked as red circle, describing its position in relation to transcription start site (TSS). CNS1 conserved non-coding sequence 1, UTR untranslated region

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