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Fig. 6 | Clinical Epigenetics

Fig. 6

From: TET1 exerts its anti-tumor functions via demethylating DACT2 and SFRP2 to antagonize Wnt/β-catenin signaling pathway in nasopharyngeal carcinoma cells

Fig. 6

TET1 suppressed NPC cells invasion by inhibiting EMT process. a Transwell assay of cell invasiveness showing cells that traversed the Matrigel-coated membrane. The analysis is shown in (b). c The expression of E-cadherin, N-cadherin, Occuldin, Vimentin, and snail1 in TET1-CD- expressing HNE1 and HONE1cells was determined by qRT-PCR. d Subcellular location and expression of E-cadherin and N-cadherin in HONE1 cells by immunofluorescence staining

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