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Table 1 Demographic variables of the cancer and control arms

From: Increased epigenetic age in normal breast tissue from luminal breast cancer patients

Variables Breast cancer
N (%)/mean (95% CI)
Controls
N (%)/mean (95% CI)
p value
Total cohort samples 40 53  
Age (years) 49.7 (46.32–53.02) 45.9 (40.29–51.55) 0.126
Age category    0.742
 < 50 years 24 (60%) 30 (57%)  
 ≥ 50 years 16 (40%) 23 (43%)  
Ethnicity    0.076
 White 31(78%) 49 (92%)  
 African Americans 4 (10%) 3 (6%)  
 Others 5 (13%) 1 (2%)  
 Ashkenazi Jew 6 (15%) 3 (6%) 0.162
Height (in.) 64.02 (63.10–64.94) 63.96 (63.19–64.73) 0.45
Weight (lbs) 157.22 (146.54–167.90) 157.50 (148.59–166.41) 0.483
BMI (kg/m2)    0.446
 < 18.5 0 (0%) 1 (2%)  
 18.5–24.9 21 (53%) 22 (42%)  
 25.0–29.9 8 (20%) 17 (32%)  
 > 30 11 (28%) 13 (25%)  
Tobacco use    0.696
 No 25 (63%) 31 (58%)  
 Yes 15 (38%) 22 (42%)  
Smoking (pack years) 3.73 (1.06–6.41) 3.86 (1.06–6.59) 0.475
Current alcohol use    0.019
 No 20 (52%) 15 (28%)  
 Yes 18 (47%) 38 (72%)  
Positive family history of breast cancer 18 (45%) 11 (21%) 0.012
Age at menarche (years) 12.37 (11.72–13.03) 12.54 (12.20–12.87) 0.671
Menopausal status    0.212
 Pre-menopausal 27 (68%) 29 (55%)  
 Post-menopausal 13 (33%) 24 (45%)  
Ever pregnant    0.266
 No 8 (20%) 16 (30%)  
 Yes 32 (80%) 37 (70%)  
No. of times pregnant 2.6 (1.94–3.25) 1.94 (1.48–2.39) 0.049
Age at first childbirth (years) 25.73 (23.24–28.99) 25.61 (24.21–27.01) 0.465
Number of live births 1.97 (1.54–2.40) 1.57 (1.23–1.92) 0.073
Breastfeeding    0.567
 No 25 (63%) 30 (57%)  
 Yes 15 (38%) 23 (43%)  
ER/PR status    NA
 ER+/PR+ 38 (95%)  
 ER+/PR- 1 (2.5%)  
 ER−/PR+ 0(0)   
 ER−/PR− 1(2.5%)  
Her2 status    NA
 Not typed 6 (15%)  
 Her− 31 (78%)  
 Her+ 3 (7.5%)