Table 3 Interaction between AXL DNA methylation at birth and PTS exposure in relation to risk of bronchitic symptoms at age 10 years in CHS subjects (N = 799) (adjusted for child’s sex, ethnicity, and city of residence at study entry. Odds ratios are scaled to per 2SD change in methylation)
| Â | Unexposed to PTS | Exposed to PTS | Interaction P value | ||
|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | ||
Region 1 | 0.96 (0.59, 1.57) | 0.87 | 1.52 (0.72, 3.20) | 0.28 | 0.46 |
Region 2 | 1.21 (0.75, 1.96) | 0.43 | 1.85 (0.87, 3.96) | 0.11 | 0.53 |
Region 3 | 1.10 (0.69, 1.76) | 0.68 | 1.35 (0.64, 2.82) | 0.43 | 0.64 |
Region 4 | 0.93 (0.58, 1.47) | 0.74 | 0.85 (0.40, 1.81) | 0.67 | 0.90 |
Region 5 | 0.76 (0.45, 1.29) | 0.31 | 2.26 (1.09, 4.72) | 0.03 | 0.01 |
Region 6 | 0.91 (0.59, 1.40) | 0.67 | 0.99 (0.46, 2.17) | 0.99 | 0.62 |