Skip to main content

Table 2 Association between PTS exposure and AXL DNA methylation at birth in CHS and NEST subjects (adjusted for child’s sex, ethnicity (of child in CHS and of mother in NEST), gestational age, maternal age at delivery, and parental education level)

From: Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes

 

CHS (N = 799)

NEST (N = 592)

Pooled analysis (N = 1294)a

훽β (95% CI)

P value

β (95% CI)

P value

β (95% CI)

P value

Region 1

− 0.49 (− 1.56, 0.58)

0.37

0.11 (− 1.16, 1.37)

0.87

− 0.30 (− 1.11, 0.51)

0.47

Region 2

0.01 (− 0.57, 0.59)

0.97

0.59 (− 0.23, 1.42)

0.16

0.23 (− 0.25, 0.72)

0.34

Region 3

0.58 (− 0.06, 1.22)

0.08

− 0.22 (− 1.48, 1.04)

0.73

0.24 (− 0.40, 0.88)

0.47

Region 4

− 0.12 (− 0.67, 0.43)

0.67

0.55 (− 0.45, 1.54)

0.28

0.14 (− 0.41, 0.69)

0.61

Region 5

0.56 (0.31, 0.82)

1.72E−05

0.35 (− 0.03, 0.73)

0.07

0.51 (0.29, 0.74)

7.89E−06

Region 6

0.46 (− 0.16, 1.09)

0.14

− 0.53 (− 1.88, 0.81)

0.44

− 0.10 (− 0.78, 0.57)

0.77

  1. Estimates are showing percent changes in methylation
  2. aPooled analysis only included black, Hispanic, and non-Hispanic white subjects