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Table 1 Sample demographic table

From: Genome-wide methylomic analysis in individuals with HNF1B intragenic mutation and 17q12 microdeletion

 

HNF1B intragenic mutation

(n = 21)

17q12 deletion

(n = 21)

Control*

(n = 21)

Median age, years (interquartile range)

10 (2–28)

9 (2–31)

9 (2–29)

Sex, n (%)

Male 8 (38)

Male 8 (38)

Male 8 (38)

Diabetes, n (%)

9 (43)

9 (43)

9 (43)

Renal abnormality, n (%)

 -Renal cysts/cystic dysplasia

12 (57)

12 (57)

8 (38)

 -Renal hyperechogenicity

2 (10)

1 (5)

2 (10)

 -Single kidney

1 (5)

1 (5)

1 (5)

 -Multicystic and dysplastic kidney

2 (10)

2 (10)

1 (5)

 -Obstruction

–

2 (10)

–

  1. The samples were matched for age, sex and diabetes status; all individuals had a serum creatinine level < 250 μmol/L
  2. *For individuals without diabetes mellitus, controls were individuals with no HNF1B gene mutation or deletion detected on genetic testing; for individuals with diabetes mellitus, controls were individuals from the UNITED (Using pharmacogeNetics to Improve Treatment in Early-onset Diabetes) study with presumed type 1 diabetes