Table 1 Percentage of WBC DNA BRCA1 and MGMT methylations
From: Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters
Total population (n = 1014) | ||
|---|---|---|
Gene | Group | Promoter methylation (%) |
BRCA1 | Control women | 25/268 (9.3) |
Delivering women | 20/295 (6.8) | |
Newborns | 30/302 (9.9) | |
Breast cancer | 5/67 (7.5) | |
Ovarian cancer | 13/82 (15.8) | |
MGMT | Control women | 35/268 (13.1) |
Delivering women | 29/295 (9.8) | |
Newborns | 37/302 (12.3) | |
Breast cancer | 10/67 (15) | |
Ovarian cancer | 17/82 (20.7) | |
Group | Methylation (%) | |
BRCA1/MGMT | Control women | 6/25 (24) |
Delivering women | 2/20 (10) | |
Newborns | 3/30 (10) | |
Breast cancer | 0 | |
Ovarian cancer | 5/17 (29.4) | |