Table 5 Paired test of within subject mean difference in methylation of individual markers observed in DRE and FV samples (N = 60)
From: A panel of DNA methylation markers for the detection of prostate cancer from FV and DRE urine DNA
Marker | Mean difference | 95% CI | p value |
|---|---|---|---|
Average methylation | 0.356 | (− 0.074, 0.786) | 0.103 |
# of positive markers | 0.667 | (− 0.421, 1.754) | 0.225 |
ADCY4 | 0.748 | (− 0.774, 2.269) | 0.329 |
AOX1rc | 1.788 | (0.479, 3.098) | 0.008 |
APC2 | 0.449 | (− 0.175, 1.072) | 0.155 |
CXCL14 | − 0.140 | (− 0.935, 0.655) | 0.725 |
EPHX3 | 0.258 | (− 1.013, 1.528) | 0.686 |
KIFC2 | 1.133 | (− 0.161, 2.426) | 0.085 |
GFRA2 | 0.766 | (0.134, 1.397) | 0.018 |
GSTP1 | 0.501 | (− 0.203, 1.204) | 0.160 |
HEMK1rc | − 0.131 | (− 1.124, 0.861) | 0.792 |
HOXA7 | 0.360 | (− 0.812, 1.531) | 0.542 |
HOXB5 | − 0.823 | (− 2.148, 0.502) | 0.219 |
HOXD10 | 0.493 | (− 0.340, 1.325) | 0.241 |
HOXD3a | 0.218 | (− 0.852, 1.288) | 0.685 |
HOXD3b | − 0.797 | (− 1.602, 0.008) | 0.052 |
HOXD9 | 0.909 | (− 0.378, 2.196) | 0.163 |
MOXD1 | 0.067 | (− 0.765, 0.899) | 0.873 |
NEUROG3 | 1.159 | (0.202, 2.116) | 0.018 |
NODAL | − 0.500 | (− 1.508, 0.508) | 0.325 |
RASSF5 | 0.312 | (− 0.575, 1.199) | 0.484 |