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Table 1 Patient demographics summarized in the overall population and by biopsy diagnosis

From: A panel of DNA methylation markers for the detection of prostate cancer from FV and DRE urine DNA

Variable

Cases (n = 42)

Controls (n = 52)

All (n = 94)

Age

n (%)

42 (100.0%)

50 (96.2%)

92 (97.8%)

Median

66

64

65.5

Mean (SD)

67.1 (7.1)

63.9 (7.6)

65.4 (7.5)

Range

48–84

50–83

48–84

PSA

n (%)

40 (95%)

51 (98.1%)

91 (96.8%)

Median

6.4

5.2

5.7

Mean (SD)

7.1 (3.3)

5.6 (2.7)

6.3 (3.1)

Range

3.26–18.92

0.63–14.9

0.63–18.92

Race

Alaskan Native

1 (2.4%)

0 (0.0%)

1 (1.1%)

Asian

0 (0.0%)

1 (1.9%)

1 (1.1%)

Black

4 (9.5%)

5 (9.6%)

9 (9.6%)

Hispanic

1 (2.4%)

1 (1.9%)

2 (2.1%)

White

36 (85.7%)

44 (84.6%)

80 (85.1%)

Missing

0 (0.0%)

1 (1.9%)

1 (1.1%)

Urine samples

DRE and FV

28 (66.7%)

32 (61.5%)

60 (63.8%)

DRE only

10 (23.8%)

17 (32.7%)

27 (28.7%)

FV only

4 (9.5%)

3 (5.8%)

7 (7.4%)

Gleason score

n

39 (92.9%)

NA

 

Median

7

  

Range

6–10

  

=6

19 (45.2%)

  

7

8 (19%)

  

> 7

13 (30.9%)

  

Missing

3 (7.1%)

  

Positive cores

n

39 (92.9%)

NA

 

Median

4

  

Range

1–12

  

≤ 3

19 (45.2%)

  

> 3

20 (47.6%)

  

Missing

3 (7.1%)

  
  1. The mean PSA for cases was calculated after excluding two outliers which were greater than two times the highest remaining PSA value from cases. All patients underwent 12-core TRUS biopsies. The number of positive cores is based on the histological examination of all 12 cores
  2. PSA prostate-specific antigen, SD standard deviation, DRE digital rectal exam, FV first void, NA not applicable