Fig. 5

Selectively reduced response of alveolar macrophages from male offspring of sepsis fathers. TNF-α cytokine levels in the supernatant of alveolar macrophages either untreated (open squares), after stimulation with LPS (200 ng/ml; light gray squares) or zymosan (250 μg/ml; dark gray squares) of male (a) or female (b) offspring. Cells were yielded by bronchoalveolar lavage of the lungs after euthanasia; n = 12 for each group, horizontal line depicts median. Group comparisons were performed by Mann-Whitney U test