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Table 3 MSigDB Pathways enriched by DMRs with nominal p < 0.05 from GREAT analysis

From: Epigenetic signature of preterm birth in adult twins

Binomial model Hypergeometric model
Term Name Rawp value FDR Fold enrichment Exp. Obs.
Gene Hits
Rawp value FDR Fold enrichment Exp. Obs.Gene Hits TotalGenes
Antigen processing and presentation 1.33e−55 1.76e−52 12.28 6.27 77 3.55e−5 9.37e−3 2.10 13.79 29 80
Graft-versus-host disease 5.65e−53 3.73e−50 14.46 4.63 67 2.17e−6 9.56e−4 2.98 6.38 19 37
Type I diabetes mellitus 1.52e−50 6.72e−48 10.20 7.65 78 1.24e-7 1.63e−4 3.11 7.07 22 41
Allograft rejection 7.25e−50 2.40e−47 12.55 5.42 68 7.10e-7 4.69e−4 3.15 6.03 19 35
Viral myocarditis 4.92e-30 8.13e−28 5.13 15.02 77 9.64e-6 3.18e−3 2.30 11.72 27 68