Table 2 Characterizations of the six identified DMRs with FWER < 0.1
DMR | Chr | Start | End | Discovery | Replication | Â | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Value | p value | FWER | Value | p value | Linked genes | Gene region | Location to CGI | ||||
1 | 5 | 1,594,282 | 1,594,863 | − 0.505 | 4.46E−07 | 0.01 | − 0.157 | 1.90E−04 | SDHAP3 | Body, TSS200, TSS1500 | Island |
2 | 3 | 111,730,545 | 111,730,545 | 1.571 | 7.92E−07 | 0.02 | 0.891 | 8.88E−05 | TAGLN3 | Body | NA |
3 | 22 | 24,384,159 | 24,384,573 | 0.455 | 2.28E−06 | 0.04 | 0.184 | 5.03E−04 | GSTT1 | 1stExon, 5′UTR, TSS200 | Island |
4 | 6 | 291,687 | 292,596 | − 0.453 | 4.26E−06 | 0.08 | 0.311 | 2.55E−05 | DUSP22 | 1stExon, 5′UTR, TSS200, TSS1500 | Island, N-Shore |
5 | 6 | 41,068,646 | 41,068,752 | − 0.512 | 4.46E−06 | 0.08 | 0.382 | 1.70E−05 | NFYA, LOC221442 | 3’UTR | Island |
6 | 5 | 135,415,258 | 135,416,613 | 0.271 | 4.90E−06 | 0.10 | 0.197 | 8.68E−06 | MIR886 | Body, TSS200, TSS1500 | Island, N-Shore, S-Shore |