Fig. 2
From: Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression
RNA sequencing data were used to analyze gene expression in PKI-587-sensitive and PKI-587-resistant sets of cell lines. a Upregulated and downregulated genes (top 20 each) in resistant cells as compared to sensitive cells. b Relative P2RY14 expression from RNAseq data. c Relative P2RY14 expression from RT-qPCR data. d Kaplan-Meier survival plot shows the overall survival benefit of ALL and AML patients. e Western blot was performed for the total cell lysate to determine phosphorylation of AKT, ERK1/2, S6K, and p38