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Table 2 FKBP5 methylation associated with cardiometabolic risk in individuals with diabetes

From: Type 2 diabetes and cardiometabolic risk may be associated with increase in DNA methylation of FKBP5

Independent variables

Model including the covariates age, sex, and race

Effect size

 

β

p

R

Effect size

Percent methylation of CpG9

 HbA1c

0.535

0.003**

0.378

Medium-large

 LDL

0.344

0.037*

0.201

Small to medium

Percent methylation of CpG7

 BMI

0.516

0.001**

0.476

Large

 WC

0.403

0.006**

0.350

Medium-large

  1. The analysis included 43 subjects. Percent methylation of CpG9 and CpG7 were the dependent variables in the model
  2. *p < 0.05; **p < 0.01
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Clinical Epigenetics

ISSN: 1868-7083

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