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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease

Fig. 3

Box plot of CpG methylation level in the MGAT3 gene promoter (assays A1 and A2) analyzed from PBMCs (a), CD3+ T cells isolated from PBMCs (b), and CD3+ T cells isolated from inflamed colonic mucosa (c) from the independent cohort of Porto. Changes between UC patients with active disease and HC were statistically significant only in CD3+ T cells isolated from inflamed colonic mucosa at CpG positions 3 and 7–12 (p < 0.05 after Bonferroni correction for 15 hypotheses). PBMC peripheral blood mononuclear cells, UC ulcerative colitis, HC healthy controls

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