|
Clinical parameter
|
RAI2 methylation status
|
P value
|
|---|
|
Unmethylated (n = 110)
|
Methylated (n = 127)
|
|---|
|
Gender
|
P = 0.0000***
|
|
Male
|
95
|
46
|
|
Female
|
15
|
81
|
|
Age (years)
|
P = 0. 5217
|
|
≥ 50
|
87
|
96
|
|
< 50
|
23
|
31
|
|
Tumor location
|
P = 0.2859
|
|
Right-sided colon
|
29
|
28
|
|
Left-sided colon
|
36
|
34
|
|
Rectum
|
45
|
65
|
|
Tumor size (cm)
|
|
< 5
|
61
|
76
|
P = 0.4951
|
|
≥ 5
|
49
|
51
|
|
TNM stage
|
P = 0.0001***
|
|
I–II
|
48
|
26
|
|
III–IV
|
62
|
101
|
|
Differentiation
|
P = 0.0841
|
|
Middle-high
|
84
|
84
|
|
Low
|
26
|
43
|
|
Lymph node metastasis
|
P = 0.0000***
|
|
Yes
|
59
|
101
|
|
No
|
51
|
26
|
|
Intravascular cancerous embolus
|
P = 0.0901
|
|
Yes
|
10
|
21
|
|
No
|
100
|
106
|
- P values are obtained from the chi-squared test
- Statistically significant *P < 0.05, **P < 0.01, ***P < 0.001
