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Fig. 3 | Clinical Epigenetics

Fig. 3

From: miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway

Fig. 3

DNMT3B expression was upregulated in breast cancers and was negatively correlated with the survival rate of breast cancer patients. a mRNA levels of DNMT3B detected by qRT-PCR in eight breast cancer tissues were higher than that in their adjacent normal tissues. b Comparison of the protein levels of DNMT3B in eight paired breast cancer and adjacent non-tumor tissues by Western blotting. c Immunohistochemistry representative photos of DNTM3B expression in normal and different immunoreactive scores breast cancer tissues. d Immunoreactive scores of DNMT3B in breast cancer and the adjacent normal tissues. e Kaplan-Meier analysis of overall survival curves for breast cancer patients with low versus high expression of DNMT3B. Data were presented as mean ± SD, *P < 0.05, ***P < 0.001

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