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Table 5 Performance of predictive CpG sets reported by Almstrup et al. in this study

From: Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

  Among COAST females (N = 30) Among COAST males (N = 25) Among COAST males and females combined (N = 55)
Specificity Sensitivity Specificity Sensitivity Specificity Sensitivity
94 puberty classifiers (N = 75) 83.3% 96.7% 92.0% 92.0% 92.7% 87.3%
133 reproductive hormonea classifiers (N = 104) 86.7% 86.2% 72.0% 96.0% 90.9% 90.9%
  1. aFollicle stimulating hormone (FSH), luteinizing hormone (LH), anti-Mullerian hormone (AMH), testosterone (T), estradiol (E2), inhibin B
  2. Numbers in parentheses in first column refer to the number of CpGs in each subset reported by Almstrup that are present in this study