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Table 4 Modules of correlated transcripts at genes near female puberty-associated DMPs are enriched for immune functions and hormone signaling

From: Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

WGCNA Module (# of genes) Pathway enrichment category (Adjusted P value) Database
1 (198) T cell receptor signaling (P = 0.0038) and activation (P = 0.0021) KEGG 2016, BioCarta 2016
Epidermal growth factor receptor (EGFR) signaling (P = 0.029) Panther 2016
2 (86) Estrogen receptor beta signaling (P = 0.0019) KEGG 2016
Androgen receptor signaling (P = 0.0067)