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Table 2 Predicted estrogen-responsive genes are over-represented near female puberty-associated DMPs. P < 2.0 × 10−6 by permutation testing

From: Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

  No. of genes with high affinity estrogen-responsive elements (%) No. of all other genes (%) Total
Near a puberty DMP 63 (20.2) 249 (79.8) 312 (100)
Near a Non-DMP 3434 (14.7) 19,883 (85.3) 23,317 (100)
Total 3497 (14.5) 20,132 (85.5) 23,629 (100)
  1. DMP, differentially methylated probe