Skip to main content

Table 3 Differentially methylated regions (DMR) in PPAT of obese/overweight PCa patients compared to normal weight controls

From: Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

DMR

Chr

Start–end (bp)

Size (bp)

P value

FDR

Located gene

DMCs*

Relation to CpG island

1

6

30,038,791–30,039,801

1010

5.11E−05

2.07E−02

RNF39

37(0)

Island

2

6

29,648,161–29,649,084

923

1.54E−03

2.08E−01

ZFP57#

22(0)

Open sea

3

17

71,228,123–71,228,832

709

3.10E−03

2.86E−01

FAM104A

4(3)

Island

4

17

71,228,123–71,228,832

709

3.10E−03

2.86E−01

C17orf80

10(8)

Island

5

12

42,720,006–42,720,167

161

5.56E−03

2.86E−01

PPHLN1

4(0)

Island

6

6

31,650,735–31,651,158

423

5.59E−03

2.86E−01

MIR4646#

16(0)

Island

7

7

27,169,674–27,170,961

1287

5.66E−03

2.86E−01

HOXA4

17(11)

Island

8

6

33,282,736–33,283,145

409

5.87E−03

2.86E−01

TAPBP

18(18)

Island

9

20

57,463,763–57,464,129

366

6.74E−03

2.86E−01

GNAS

15(0)

Island

10

16

86,546,938–86,547,322

384

7.03E−03

2.86E−01

FOXF1

4(0)

Shore

  1. #The DMR is located at the intergenic region
  2. Chr chromosome
  3. *The number in the bracket is the quantities of DMCs located at the promoter (TSS200 and TSS1500) regions