Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

Table 1 Clinicopathological characteristics of PCa patients by BMI category

Character	NW (n = 5)	OB/OW (n = 5)	P value
Age (years)	65.2 ± 3.8	63.2 ± 2.5	0.67^a
BMI (kg/m²)	23.0 ± 0.3	29.0 ± 0.9	0.0003^a
Gleason score
< 7	2 (40%)	1 (20%)
≥ 7	3 (60%)	4 (80%)	1.00^b
Stage
OCPCa	2 (40%)	2 (40%)
EPCa	3 (60%)	3 (60%)	1.00^b
Smoking status
Yes	1	5
No	4	0	0.05^b
PSA (ng/ml)	10.7 ± 2.7	12.1 ± 3.23	0.74^a

Data are presented as mean ± SD or number (%). Significant difference between OB/OW and NW was evaluated using ^at test and ^bFisher’s exact test
OB/OW obese/overweight, NW normal weight, BMI body mass index; PSA, prostate specific antigen; PCa, prostate cancer; OCPCa, organ-confined prostate cancer; EPCa, extra-prostatic PCa

ISSN: 1868-7083