Skip to main content

Table 1 Descriptive characteristics of study participants in Project Viva with information on DNA methylation and mid-childhood IgE

From: Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach

Participant characteristics Cord blood DNA methylation data (N = 242) Mid-childhood DNA methylation data (N = 411) DNA methylation data at both time points (N = 217)
Maternal characteristics
Age (years), mean ± SD 32.0 (5.6) 32.3 (5.5) 32.3 (5.4)
Smoking status, N (%)
 Smoked during pregnancy 24 (10%) 41 (10%) 20 (9%)
 Former smoker 53 (22%) 83 (20%) 49 (23%)
 Never smoker 165 (68%) 287 (70%) 148 (68%)
College graduate, N (%)
 Yes 158 (65%) 271 (66%)* 144 (66%)
 No 84 (35%) 138 (34%) 73 (34%)
Atopy history
 Yes 90 (37%) 163 (40%)* 80 (37%)
 No 152 (63%) 246 (60%) 137 (63%)
Child characteristics
Gestational age (weeks), mean ± SD 39.7 (1.6) 39.6 (1.6) 39.7 (1.6)
Age at blood drawn (years), mean ± SD 7.8 (0.7) 7.8 (0.7) 7.8 (0.7)
Sex, N (%)    
 Female 117 (48%) 201 (49%) 105 (48%)
 Male 125 (52%) 210 (51%) 112 (52%)
Race/ethnicity, N (%)
 White 161 (67%) 256 (62%) 143 (66%)
 Black 42 (17%) 77 (19%) 39 (18%)
 Other 39 (16%) 77 (19%) 35 (16%)
Total serum IgE level in mid-childhood, (kU/L) 146.4 (310.2) 152.1 (286.2) 142.5 (311.0)
  1. *Number of missing = 2
  2. Number of missings = 1