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Fig. 4 | Clinical Epigenetics

Fig. 4

From: A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples

Fig. 4

Unsupervised analyses performed on GSE48684 including the 518 DMPs shared by EPIC and 450K arrays. a Unsupervised hierarchical clustering and heatmap based on these 518 DMPs. Each column represents one tumor or mucosa sample from GSE48684, and each row represents one CpG. The dendrogram was computed and reordered based on row means. Methylation values are displayed from 0 (red, unmethylated) to 1 (green, fully methylated). b Clustering using multidimensional scaling (MDS) on tumor and mucosa samples from GSE48684 based on these 518 DMPs

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