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Fig. 4 | Clinical Epigenetics

Fig. 4

From: The neuropeptide genes SST, TAC1, HCRT, NPY, and GAL are powerful epigenetic biomarkers in head and neck cancer: a site-specific analysis

Fig. 4

Kaplan-Meier survival curves for the 230 patients with HNSCC, according to the methylation status of the five target genes. Disease-free survival for a SST, b TAC1, c HCRT, d NPY, and e GAL in the case of methylated (red lines) and unmethylated (blue lines) genes. f Joint analysis of the five genes. Blue line: patients with 0–2 methylated genes; red line: patients with 3–5 methylated genes. A probability of < 0.05 (*P < 0.05) was considered to represent a statistically significant difference

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