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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer

Fig. 6

Q-Q plots of the 22 p values for the 5-year OS analysis. Under the null hypothesis of no association, p values follow a uniform distribution between 0 and 1. The diagonal line shows this expected distribution of p values. The points on the plot show the p values observed in the survival analysis. For all breast adenocarcinomas together (panel a) and only the ductal adenocarcinomas (panel b), the presence of many points above the diagonal line indicates a substantial enrichment in low p values. The p values in the lobular subset (panel c) are closely following the expected distribution of the p values, indicating no enrichment in low p values there

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