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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Placental surface area mediates the association between FGFR2 methylation in placenta and full-term low birth weight in girls

Fig. 2

The mediation effects. Girls (a) and boys (b). θ1 is the estimated effect (ln OR) of CpG 11 methylation on FT-LBW adjusting for confounders. θ1’ is the estimated effect (ln OR) of CpG 11 methylation on FT-LBW additionally introducing placental surface area into model. θ2 is the estimated effect (ln OR) of placental surface area on FT-LBW adjusting for confounders. β1 is the coefficient of CpG 11 methylation on placental surface area. Confounders include maternal age, education, family monthly income, ETS exposure during pregnancy, and gestational age. *P value < 0.05; **P value < 0.01

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