Table 4 Genome-wide measures of altered DNAm in high-risk MTHFR and reference placentas
From: No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation
|  | Array-wide average DNAm (β) | Outlier array sites (%) | Alu DNAm (%) | LINE-1 DNAm (%) | rDNAm (%) |
|---|---|---|---|---|---|
Reference (N = 10) | 0.407 (0.396–0.413) | 0.661 (0.262–0.993) | 18.9 (17.6–21.7) | 52.8 (51.0–53.8) | 19.4 (11.2–30.9) |
High-risk 677 (N = 10) | 0.405 (0.397–0.409) | 0.851 (0.262–6.357) | 20.1 (15.7–21.4) | 53.5 (49.8–57.6) | 20.0 (8.4–28.9) |
High-risk 1298 (N = 10) | 0.405 (0.395–0.413) | 1.14 (0.501–3.37) | 19.8 (17.5–21.6) | 51.0 (46.5–55.0) | 22.9 (10.2–28.9) |