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Table 1 Clinical characteristics of cases

From: No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation

 

N

Sex; N male (% male)

Gestational age (weeks); median (range)

Maternal age (years); median (range)

Control

179

85 (47)

39.6 (19.4–41.9)

34.4 (23.8–42.7)

EOPE

28

17 (61)

32.7 (23.6–38.4)*

36.0 (19.7–42.9)

LOPE

20

10 (50)

38.5 (34.9–41.4)*

34.3 (26.1–41.5)

nIUGR

21

9 (42)

36.2 (24.0–40.6)*

34.5 (26.1–42.8)

NTD

55

28 (51)

21.0 (16.7–23.7)*

30.4 (17.7–40.6)*

  1. EOPE early-onset preeclampsia, LOPE late-onset preeclampsia, nIUGR normotensive intrauterine growth restriction, NTD neural tube defect
  2. *p < 0.05, calculated in comparison to the control group by Fisher’s exact test for categorical variables and Mann-Whitney test for continuous variables
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Clinical Epigenetics

ISSN: 1868-7083

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