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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

Fig. 2

Regional DNA methylation differs in parenchymal fibroblasts isolated from donors with COPD versus non-COPD. a Summary of regional DNA methylation differences between DNA isolated from donors with and without COPD. Circle size represents the number of probes per regions. Orange = hypomethylated in COPD samples, blue = hypermethylated in COPD. b–d Detailed plots of the three regions with a maximum difference in DNA methylation between DNA isolated from donors with and without COPD of greater than 20% (beta value difference of 0.2)

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