Table 4 All significant gene expression correlations associated with the 340 significantly differentially methylated sites in transcriptional cluster 3 placentas (N = 5) compared to transcriptional cluster 1 placentas (N = 19), corrected for fetal sex and gestational age at delivery
From: Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia
Probe | Gene | Locationa | Enhancer | Pearson r | FDR q value |
|---|---|---|---|---|---|
cg03983223 | WIPF1 | 1stExon-open sea | FALSE | − 0.74 | 4.45E-03 |
cg05544807 | DNMT3A | Body-island | FALSE | − 0.73 | 4.45E-03 |
cg22462240 | LGALS3BP | IGR-open sea | FALSE | − 0.74 | 4.45E-03 |
cg18275589 | DAB2 | IGR-shelf | FALSE | − 0.72 | 5.02E-03 |
cg09258479 | PDZK1IP1 | TSS200-open sea | FALSE | − 0.69 | 7.40E-03 |
cg07593977 | CTSB | IGR-open sea | TRUE | − 0.69 | 7.40E-03 |
cg24506086 | TEAD1 | Body-open sea | TRUE | − 0.66 | 1.40E-02 |
cg17850498 | ECE1 | Body-open sea | TRUE | − 0.65 | 1.65E-02 |
cg07349094 | AFF3 | 1stExon-open sea | FALSE | 0.64 | 1.65E-02 |
cg03821121 | MICAL2 | 5′UTR-open sea | TRUE | − 0.65 | 1.65E-02 |
cg04885072 | MGST1 | Body-open sea | TRUE | 0.63 | 1.94E-02 |
cg00874480 | MGST1 | Body-open sea | TRUE | 0.62 | 2.45E-02 |
cg11535839 | FOSL2 | IGR-open sea | FALSE | − 0.61 | 2.59E-02 |
cg05305434 | LSP1 | TSS200-open sea | FALSE | − 0.61 | 2.72E-02 |
cg23170988 | SNCG | Body-open sea | FALSE | − 0.60 | 3.17E-02 |
cg05929019 | LAMC2 | TSS200-open sea | FALSE | − 0.59 | 3.75E-02 |
cg15300730 | ZFP36L2 | TSS1500-shore | FALSE | − 0.58 | 3.75E-02 |
cg22234930 | PKM | 5′UTR-shelf | FALSE | − 0.58 | 3.83E-02 |