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Table 3 Top 20 significant gene expression correlations associated with the 8763 significantly differentially methylated sites in transcriptional cluster 2 placentas (N = 19) compared to transcriptional cluster 1 placentas (N = 19), corrected for fetal sex and gestational age at delivery

From: Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Probe Gene Locationa Enhancer Pearson r FDR q value
cg23677911 GALNT2 Body-open sea True − 0.81 3.53E-06
cg26333638 HEXB Body-shore False − 0.81 3.53E-06
cg04858987 SH3BP5 Body-open sea True − 0.78 1.34E-05
cg13553455 COL17A1 TSS1500-open sea False − 0.78 1.34E-05
cg16557964 TMEM45A 5′UTR-open sea True − 0.77 1.68E-05
cg19140548 SH3PXD2A Body-open sea True − 0.77 2.50E-05
cg15700009 LDHA TSS1500-shore False − 0.76 2.70E-05
cg23730027 FLNB Body-island False − 0.76 2.93E-05
cg18444702 SH3BP5 Body-open sea True − 0.75 4.27E-05
cg17338821 FLNB Body-shore True − 0.75 5.14E-05
cg25549791 GALE TSS200-shore False − 0.74 5.49E-05
cg14019050 ABCA1 TSS1500-island False − 0.74 5.49E-05
cg19512693 FLT1 Body-open sea True 0.74 6.15E-05
cg04704064 SCARB1 IGR-island False 0.74 6.29E-05
cg00411097 TMEM184A 1stExon-open sea True − 0.73 7.24E-05
cg11079619 INHBA 5′UTR-shelf False − 0.73 7.32E-05
cg00513984 SCARB1 IGR-island False 0.73 7.32E-05
cg26509870 PHYHIP IGR-shelf False − 0.73 8.19E-05
cg06531595 PDE5A Body-open sea True − 0.72 9.89E-05
cg18874575 ZNF559 3′UTR-open sea False 0.72 9.89E-05
  1. aTSS transcription start site, IGR intergenic region, UTR untranslated region