Table 3 Top 20 significant gene expression correlations associated with the 8763 significantly differentially methylated sites in transcriptional cluster 2 placentas (N = 19) compared to transcriptional cluster 1 placentas (N = 19), corrected for fetal sex and gestational age at delivery
From: Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia
Probe | Gene | Locationa | Enhancer | Pearson r | FDR q value |
|---|---|---|---|---|---|
cg23677911 | GALNT2 | Body-open sea | True | − 0.81 | 3.53E-06 |
cg26333638 | HEXB | Body-shore | False | − 0.81 | 3.53E-06 |
cg04858987 | SH3BP5 | Body-open sea | True | − 0.78 | 1.34E-05 |
cg13553455 | COL17A1 | TSS1500-open sea | False | − 0.78 | 1.34E-05 |
cg16557964 | TMEM45A | 5′UTR-open sea | True | − 0.77 | 1.68E-05 |
cg19140548 | SH3PXD2A | Body-open sea | True | − 0.77 | 2.50E-05 |
cg15700009 | LDHA | TSS1500-shore | False | − 0.76 | 2.70E-05 |
cg23730027 | FLNB | Body-island | False | − 0.76 | 2.93E-05 |
cg18444702 | SH3BP5 | Body-open sea | True | − 0.75 | 4.27E-05 |
cg17338821 | FLNB | Body-shore | True | − 0.75 | 5.14E-05 |
cg25549791 | GALE | TSS200-shore | False | − 0.74 | 5.49E-05 |
cg14019050 | ABCA1 | TSS1500-island | False | − 0.74 | 5.49E-05 |
cg19512693 | FLT1 | Body-open sea | True | 0.74 | 6.15E-05 |
cg04704064 | SCARB1 | IGR-island | False | 0.74 | 6.29E-05 |
cg00411097 | TMEM184A | 1stExon-open sea | True | − 0.73 | 7.24E-05 |
cg11079619 | INHBA | 5′UTR-shelf | False | − 0.73 | 7.32E-05 |
cg00513984 | SCARB1 | IGR-island | False | 0.73 | 7.32E-05 |
cg26509870 | PHYHIP | IGR-shelf | False | − 0.73 | 8.19E-05 |
cg06531595 | PDE5A | Body-open sea | True | − 0.72 | 9.89E-05 |
cg18874575 | ZNF559 | 3′UTR-open sea | False | 0.72 | 9.89E-05 |