Fig. 5

a The relative expression of DNMT1, UHRF1, and USP7 in 40 primary HB and three HB cell lines (depicted in gray) compared to the mean of seven normal liver tissues are given. b Overall survival was calculated as time from diagnosis to death of the disease and is plotted for 40 HB patients. Statistical significance was calculated using the Mantel-Cox test. c Individual UHRF1 expression levels of 40 primary HBs are shown with the occurrence of important clinicopathological characteristics depicted as black boxes below. Inset: Expression levels of UHRF1 and HHIP in primary tumor tissues (dark blue dots) and tumor cell lines (light blue dots) were plotted against each other, and Spearman’s rank correlation was performed